Moderation: Klaus-Peter Jäckel
At the turn of the century it was hardly possible for women to penetrate the domains of men. Abitur and university studies were largely a male privilege. With acquired knowledge, a lot of persistence, a high degree of moral courage and immense hard work, some women achieved the highest educational qualifications. Not infrequently they came from wealthy families and often had male colleagues as sponsors. Some women worked as teachers, but only a few found their way into the natural sciences. Today we will talk about such strong women who have left their mark on the natural sciences - but also about women who failed and whose life-long work was not recognized and appreciated.
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Moderator: still open
Diabetes is a widespread disease. About 10% of German citizens and about 6% of the world population suffer from it. The basics of the disease, the consequential damage as well as the treatment options and therapy goals are discussed.
The peptide hormone insulin plays a central role in this disease. The discovery of the hormone, its structural elucidation and other milestones in 100 years of insulin research are presented. Based on an estimate of the demand for insulin, various options for its industrial production are addressed, particularly the biotechnological one. The terms 'genetic engineering' and 'biotechnology' are defined.
The genetic engineering of human insulin is a success story. The large-scale production is explained using the example of the production of human insulin in E. coli strains; the basics of biotechnological processes and protein biosynthesis are explained.
The genetic engineering of insulin analogues led to new active substance molecules with an improved profile of action being made available to diabetics. In addition, newer therapeutic approaches to diabetes treatment are presented. Some aspects of the topic ?How does pharmaceutical research work?? will be addressed.
last modified: 22.05.2022 17:56 H from W.Gerhartz